NON-PHARMA PROGRAMME

Series 2 Compounds

Series 2 compounds are the basis of new coatings for medical devices such as catheters and orthopaedics.

A lead representative of Series 2 (KLS-219) shows the core architecture of this series.

A single ruthenium-nitrogen complex is bonded to two ligands, each of which can be varied to subtly alter the properties of these compounds. 

With a distinct, and also novel, mode of action compared to Series 1 molecules, Series 2 compounds are dedicated to the development of antibacterial coatings and additives. 

MetalloBio has generated proprietary formulations for use on catheters and other medical devices.